From DNA marks to RNA control: A new clue to acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive blood cancer in which abnormal, immature cells build up in the bone marrow, disrupting the production of healthy blood cells. Now, a new study, led by Dr. José Luis Sardina's group at the Josep Carreras Leukaemia Research Institute (IJC), examines how two systems that help control normal blood cell development are connected: the chemical marks on DNA and the regulation of RNA, which carries instructions for making proteins. The work is published in the journal Science Advances.