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Results for “midterm results”

Combining HIV prevention and addiction treatment in mobile clinics could save lives

Results from a clinical trial in five major United States cities show that delivering integrated HIV and substance use disorder (SUD) services using peer navigation in mobile medical units reduced all-cause deaths by 71% compared with those among participants who received peer navigation to community-based services alone. While scientists found no difference in the use of daily, oral preexposure prophylaxis (PrEP) and medication for opioid use disorder (MOUD) between the groups, the secondary outcome of reduced mortality was significant. The study is published in JAMA Psychiatry.

Medical Xpress · 18h ago
Proning and high-frequency oscillation may not reduce duration of ventilation for children with lung injury

A treatment that is part of standard care for adults with acute respiratory distress syndrome does not provide the same benefit in children. Children with severe acute lung injury placed in the prone position do not spend less time dependent on a ventilator. High-frequency oscillatory ventilation does not shorten the duration of mechanical ventilation either. This is shown by a worldwide study led, among others, by UMCG pediatric intensivist Dr. Martin Kneyber. The results were published in The Lancet.

Medical Xpress · 22h ago
Digital therapy offers new way to prevent worsening anxiety around childbirth

Pregnant women with undiagnosed anxiety could benefit from a new digital therapy, according to a clinical trial led by King's College London. Published in JAMA Network Open, the results from the REducing Levels of AnXiety (RELAX) study have shown that self-led digital therapy significantly reduced participants' pre- and post-birth anxiety compared with participants who received usual care.

Medical Xpress · Nov 4
What the latest on mRNA vaccines means for cancer

One patient in a small trial is experiencing the fantasy results so far with an mRNA pancreatic cancer vaccine. She shows no evidence of the cancer that was supposed to kill her years ago.

NPR · Nov 2
Hereditary lung and liver disease successfully treated for the first time using gene correction

Alpha-1 antitrypsin deficiency (AATM) is a congenital metabolic disorder. It is caused by a genetic defect, which results in the protective protein alpha-1 antitrypsin (AAT) being produced incorrectly. This deficiency primarily damages the lungs and the liver, where it can lead to serious conditions such as pulmonary emphysema, liver fibrosis or cirrhosis. In particularly severe cases, an organ transplant is the last resort. There is as yet no curative treatment.

Medical Xpress · Nov 2
Researchers identify strategy for overcoming resistance to RAS-targeted cancer drugs

Researchers at Roswell Park Comprehensive Cancer Center have identified a promising strategy for overcoming one of the biggest challenges facing KRAS-targeted cancer therapies: treatment resistance. Results of the preclinical study, led by Roswell Park faculty members Vishnu Kumarasamy, Ph.D., Agnieszka Witkiewicz, M.D., and Erik Knudsen, Ph.D., were published in Cancer Research.

Medical Xpress · Nov 2