Finding new drugs requires screening vast numbers of compounds to identify those that interact with a biological target. DNA-encoded libraries (DELs) help researchers explore these large collections by attaching a short DNA sequence to each molecule, acting as a molecular barcode that allows compounds with promising properties to be identified.
Science
Research, space and the environment
Science, page 3
College students say they use AI mostly for learning and don't use it to cut corners but think that their peers do, according to the inaugural Dartmouth AI Survey, a new multiyear survey on how AI is shaping students' learning and career readiness.
Quantum researchers are searching for a topological superconductor—a material that, if discovered, would allow major advances in quantum computing by combining two distinct "flavors" of superconductivity.
Varying crop rotations and keeping the soil constantly covered with vegetation help protect crops against droughts and floods, in addition to increasing productivity. This technique was tested in Rio Grande do Sul state, Brazil, by researchers from the Center for Carbon Research in Tropical Agriculture (CCARBON) at the University of São Paulo (USP).
In space, no one can hear you scream, a bit like the empty theater screens that some horror franchise's final installments limp. But there are still some real gems among the space-based frightfests.
Global cities are subsiding by up to several inches a year, an exhaustive new survey shows
Every day, two NASA space instruments known as the Orbiting Carbon Observatory-2 and -3 (OCO-2 and OCO-3) capture more than a million observations of sunlight reflecting off Earth's surface. Using the physics of how light travels through the air, an algorithm converts these raw data into atmospheric carbon dioxide (CO₂) concentrations.
Replacing commonly used diversity, equity and inclusion-related terminology such as "belonging" with carefully matched alternative language may improve Republicans' favorability toward diversity training, according to new research from the ILR School.
The earliest spoken-word recordings of Louisiana Creole, a uniquely American language at risk of extinction, have been uncovered and analyzed for the first time, shedding light on a tongue that defined the docks and saloons of New Orleans for well over a century.
In beef cattle production, determining the ideal time to sell makes all the difference in a producer's costs. This is because, once an animal reaches its natural growth limit, it stops gaining weight significantly. From that point on, every additional day in a feedlot means spending money on feed without gaining meat in return.
A doctoral dissertation by Andrea Porcheddu, MSc in the field of Technical Physics will be examined at the Faculty of Science, Forestry and Technology, Kuopio campus.
More than 107,000 species are used and traded worldwide, more than double previous estimates, according to new research that suggests the true scale may be far greater due to major gaps in trade and wildlife collection data.
Rocketry pioneer Jack Parsons engaged in an elaborate series of occult ceremonies intended to summon an otherworldly feminine goddess into physical existence.
Richard Dawkins’ first work has thrilled fans and frustrated critics for five decades. The science has moved on, but any writer looking to supplant its place must learn its lessons Richard Dawkins’ The Selfish Gene was not predicted to be a success. Its initial print run, published this week in 1976, was just 5,000. It went on to sell millions, and is perhaps the most influential work of pop-science ever. For 50 years, it has been the go-to resource for the layperson seeking to understand evolution. What accounts for its enduring power? Prof Dawkins’ central claim, that “we are survival machines – robot vehicles blindly programmed to preserve the selfish molecules known as genes” was provocative, stripping the messy stuff of human and other life down to a simple law. And yet the book is primarily concerned with proving that complex, selfless behaviour such as altruism in animals can emerge from these basic “selfish” drives, satisfyingly resolving an apparent paradox. Prof Dawkins – a zoologist by training – also succeeded in conjuring entertaining, vividly drawn vignettes of the lives of animals, from lions and ants to hawks and honeybees, to make his points. Do you have an opinion on the issues raised in this article? If you would like to submit a response of up to 300 words by email to be considered for publication in our letters section, please click here . Continue reading...
Software known as STRmix was instrumental in identifying Mr. Bundy’s DNA in a decades-old sample.
Magical versions of today's private investigators found themselves on the wrong side of the law in one English city some 400 years ago, according to research by a University of Southampton historian.
Copper is essential for making bronze, which shaped tools, weapons and ornaments across Bronze Age Europe. While many Bronze Age mines have been identified throughout Europe, researchers are still trying to pin down which of them were most active at different times and how far their copper traveled. New research, published in the journal Antiquity, suggests that a series of mines in modern-day Spain and Portugal may have been an important source of copper in the Late Bronze Age, with some of that copper ending up as far away as Scandinavia.
People who had no recollection of a lucid dream over the past three years developed the skill after one month of performing a novel training regimen twice a week, neuroscientists report.
In 2016, a binary star system emitting unusually strong gamma rays was discovered in our galactic neighborhood. Now, astronomers have found the smoking gun, or rather, a smoking trail of cool molecular gas that suggests jets emanating from a microquasar—one of the few known outside the Milky Way—are responsible.
Offer your employees money to quit and the ones who say no will work harder as a result. Researchers at the University of Waterloo, Wilfrid Laurier University and McMaster University set out to test whether pay-to-quit programs work as intended. Their results confirmed they do and revealed a benefit that nobody anticipated.



















