Results for “neurological symptoms”

The New England Journal of Medicine has published a study on the long-term efficacy of AAV8-mediated gene therapy (GNT0003) in patients with Crigler-Najjar syndrome, an extremely rare congenital liver disorder affecting approximately 500 people in Europe. It is caused by a deficiency of UGT1A1, an enzyme required for bilirubin metabolism. The accumulation of this substance can lead to irreversible neurological damage and, in the most severe cases, death.

Long COVID—or new-onset symptoms or worsening health conditions after SARS-CoV-2 infection—can lower quality of life. Finding a way to prevent it would be a welcome relief for those worried about the long-term effects of the viral infection.

A particular signaling protein in the brain could be a therapeutic target for neurological disorders arising from the deletion of the autism-linked gene MEF2C, University of Illinois Urbana-Champaign researchers found in a new mouse study published in the journal Proceedings of the National Academy of Sciences.

A research team led by Dr. Sheng Nengyin of the Kunming Institute of Zoology (KIZ) of the Chinese Academy of Sciences has reframed ZC4H2-associated rare disorder (ZARD)—a disorder marked by intellectual disability, developmental delays, muscle weakness and other neurological or physical abnormalities—as a "disease spectrum" rather than a condition driven by a single mechanism.

Parkinson's disease (PD) is a neurodegenerative condition associated with worsening tremors, slowed movements, changes in walking and speech, muscle rigidity and postural instability. Many of its symptoms are associated with a progressive loss of dopamine-producing neurons in a brain region called the substantia nigra pars compacta.

Knee osteoarthritis (OA) is the most common type of arthritis, affecting about 528 million adults worldwide.

Patients with early-onset Alzheimer's disease, whose symptoms start before age 65, have more extensive deposits of tau, a hallmark protein of the condition, compared with patients whose symptoms start at 65-plus, a new study found. What's more, tau accumulates at more than twice the rate in younger compared to older patients and spreads widely throughout the brain.

Kenya has released five Ebola patients after they tested negative for the virus and showed no symptoms

One doesn't have to step onto a football field to get a concussion; it can happen anywhere. A fall during an everyday activity or a minor car accident can deliver the jolt to the head that causes one. While headaches, memory problems, disrupted sleep and difficulty concentrating usually fade without a trace, up to 30% of people continue to experience these symptoms for years.

Getting the right diagnosis isn't always easy. Some illnesses develop slowly, some have vague symptoms and many can be mistaken for something else.

Pregnant patients receiving medication to treat opioid use disorder should not reduce their medication dose out of fear that it will worsen withdrawal symptoms in their newborns, according to a new study led by researchers at the University of Maryland School of Medicine (UMSOM).

Getting concussed is usually obvious: there's dizziness, headache and confusion. The symptoms appear after a blow to the head or body and temporarily disrupt brain function.

A defining feature of Alzheimer's disease is the abnormal, sustained accumulation of protein aggregates such as tau inside brain cells, which disrupts the cells' normal functions. As time passes, brain cells stop working and die, leading to a gradual decline in memory and thinking skills and other symptoms of this condition.

University of Pittsburgh and UPMC researcher-clinicians have uncovered why many pulmonary hypertension patients report symptoms of cognitive decline.

Spread through the bite of Aedes mosquitoes, dengue is a viral infection that can cause anything from mild fever, flu-like symptoms and joint pain to a severe form known as dengue hemorrhagic fever. What makes dengue particularly unusual and dangerous is that a second infection with a different strain, or serotype, can sometimes lead to more severe disease rather than stronger immunity.

Flu activity is higher than usual for this time of year, according to the CDC, so NBC News medical contributor, Dr. Akshay Syal, joins TODAY with tips to stay healthy. He discusses why there’s an early uptick in numbers, how to protect against the strain that is circulating, and how to manage your symptoms if you do get the flu.

A research team led by associate professor Yasuo Murayama of Kanazawa University has identified longitudinal associations among loneliness, depressive symptoms and social behaviors in children affected by the 2024 Noto Peninsula earthquake.

Parkinson's disease (PD) is a neurodegenerative condition that causes the progressive loss of dopamine-producing neurons in a brain region called the substantia nigra. Its characteristic symptoms include tremors, slowed movements, rigid muscles and difficulties with balance.

Retired NFL players may have a high risk of undiagnosed, untreated coronary artery disease (CAD) that often occurs without symptoms, according to new, independent, preliminary research presented at the American Heart Association's Scientific Sessions 2026, held Nov. 6–9 in Chicago.

Complex menopause has severe, sudden symptoms and happens due to medical interventions.

Sen. Chris Murphy is expected to fully recover from his stroke. The acronym BE FAST can help you remember the symptoms of stroke and what to do when it happens: Call 911 quickly.

For the first time in a dozen years, a leading OB-GYN group has updated its guidance on managing hot flashes, night sweats, sleep changes and other disruptive symptoms that often come along with menopause

Millions of people in the U.S. are affected by diabetic retinopathy, a complication of diabetes that affects the eyes. The condition is caused by damage to the blood vessels in the retina, the light-sensitive tissue at the back of the eye. At first, diabetic retinopathy might not cause any symptoms, or the problems might be mild. However, if the underlying diabetes remains poorly managed, it can lead to blindness.

The syndrome can make people feel like a "hibernating bear," says Dr. Norman Rosenthal, who published the first research on SAD. He explains how to identify the symptoms and what to do to feel better.

Up to three-quarters of all women will experience a genital yeast infection at least once in their lives. Recurrent infections, in particular, can significantly impair quality of life. The typical symptoms—such as itching, burning, and pain—are caused not only by the yeast Candida albicans, but, more importantly, by an excessive immune response. But why is the immune reaction in these cases so intense and persistent? An international research team led by the Leibniz-HKI has now uncovered how the host protein albumin fuels the inflammatory cascade while simultaneously shielding the fungal pathogen from the immune system. The findings have been published in Nature Communications.

Persistent fatigue, shortness of breath, difficulty concentrating, anxiety or low mood: Many people continue to suffer from symptoms months after a COVID-19 infection, significantly restricting their daily lives. However, reliable data on which treatments are effective remain scarce.

UT research shows how personal life stories can support treatment and personal recovery. Who are you, what has shaped you, and how do you see your future? For people with personality disorders, these questions can play an important role in their recovery. Ph.D. research by clinical psychologist and psychotherapist Silvia Pol shows that paying attention to personal life stories can help guide treatment decisions and support personal recovery.

More than a quarter of Americans have exaggerated or made up symptoms to try to get antibiotics from their doctor, either for themselves or for their children, a new study has found. The survey of nearly 1,000 people nationwide uncovered common motivations for misrepresenting symptoms, including feeling very sick or needing to return to work or school.

Doctors are finding vitamin D deficiency is increasingly widespread in the UK, especially in young people. But the symptoms are difficult to spot and can be missed.

Christina Applegate's MS misdiagnosis highlights how brain lesions and common symptoms can mislead doctors, with nearly one in five referrals wrong.

Hollie Sharman shares her experience of health anxiety and a doctor advises on how to manage symptoms.

Jim LaValle explains why a blood test should come before buying ashwagandha, magnesium or zinc supplements to address fatigue and other symptoms.

Some people can carry bacteria in their nose or throat without getting sick, but can spread it to others.

Before actor Eric Dane died after a two-year battle with ALS in Feb. 2026, he shared details about life with ALS and how the illness progressed.

This is a MedPage Today story. Erica Hayes, 40, has not felt healthy since November 2020 when she first fell ill with COVID. Hayes is too sick to work, so she has spent much of the last 4 years sitting on her beige couch, often curled up under an electric blanket. "My blood flow now sucks, so my hands and my feet are freezing. Even if I'm sweating, my toes are cold," said Hayes, who lives in Western Pennsylvania. She misses feeling well enough to play with her 9-year-old son or attend her 17-year-old son's baseball games. Along with claiming the lives of 1.2 million Americans, the COVID-19 pandemic has been described as a mass disabling event. Hayes is one of millions of Americans who suffer from long COVID. Depending on the patient, the condition can rob someone of energy, scramble the autonomic nervous system, or fog their memory, among many other symptoms. In addition to the brain fog and chronic fatigue, Hayes' constellation of symptoms includes frequent hives and migraines....