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Results for “two-shot penalty”

Two 'forever chemicals' associated with higher risk of aggressive breast cancer in analysis

Women with higher blood levels of two common per- and polyfluoroalkyl substances, also familiarly known as PFAS, were more likely to develop estrogen receptor-negative, or ER-negative, breast cancer, according to a new study by the National Institutes of Health (NIH), part of the U.S. Department of Health and Human Services (HHS). PFAS are a large group of chemicals used in common consumer products. Often referred to as "forever chemicals," PFAS do not break down easily in the environment and can remain in the body for years.

Medical Xpress · 1h ago
CVS Health Plans to Split Into Two Separate Companies

CVS Health says it is splitting in two, putting its retail pharmacy in one unit and its insurance side, which oversees Aetna and Caremark, will be separate. The CEO says the idea is to help customer engagement, affordability and care coordination.

NBC News · 5h ago
Scientists use AI to develop bird flu vaccine that outperforms current stockpiled shot

A University of Cambridge team has had a third success with its AI-guided technique for designing vaccines against highly infectious viruses that threaten animal and human health. Its new broad-spectrum bird flu vaccine gave complete protection against globally circulating, diverse variants of the disease in animal trials.

Medical Xpress · 6h ago
One gene, two paths: Opposite synaptic defects linked to same intellectual disability

A research team led by Dr. Sheng Nengyin of the Kunming Institute of Zoology (KIZ) of the Chinese Academy of Sciences has reframed ZC4H2-associated rare disorder (ZARD)—a disorder marked by intellectual disability, developmental delays, muscle weakness and other neurological or physical abnormalities—as a "disease spectrum" rather than a condition driven by a single mechanism.

Medical Xpress · 6h ago
Maternal vitamin A deficiency may increase risk of larger babies

A study in Norway has identified a link between a mother's vitamin A levels and her baby's birth weight. The study shows that over 43% of the women had low vitamin A levels during the latter part of their pregnancy. While almost no one had levels classified as a severe vitamin A deficiency, two out of five had insufficient levels. The study examined 723 women who experienced entirely normal pregnancies.

Medical Xpress · 9h ago
Simple text reminders could help close London's bowel cancer screening gap

As low-cost and straightforward an intervention as automated text messaging could make a significant contribution to tackling London's below-average bowel cancer screening rates, according to a study led by the University of Surrey. The project compared two approaches to encourage people who didn't respond to their initial invitation to complete their cancer screening.

Medical Xpress · 17h ago
From DNA marks to RNA control: A new clue to acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive blood cancer in which abnormal, immature cells build up in the bone marrow, disrupting the production of healthy blood cells. Now, a new study, led by Dr. José Luis Sardina's group at the Josep Carreras Leukaemia Research Institute (IJC), examines how two systems that help control normal blood cell development are connected: the chemical marks on DNA and the regulation of RNA, which carries instructions for making proteins. The work is published in the journal Science Advances.

Medical Xpress · Nov 4
New CRISPR proteins expand editing access to heart disease genes

Rice University's Han Xiao has used his AI-supported Sequence Display technology to expand the targeting abilities of CRISPR/Cas9. In a paper recently published in Nature Communications, Xiao evolved several variants of a compact Cas9 that could efficiently target stretches of DNA previously inaccessible for editing. The research included a proof-of-concept study in which the evolved Cas9s were successfully used to edit two genes found in coronary heart disease.

Medical Xpress · Nov 4
A vulnerability in liver tumor cells' nuclear gateways could pave the way for new treatments

A study led by the Cell Cycle and Cancer Group at the Vall d'Hebron Institute of Oncology (VHIO) has identified a vulnerability in liver cancer that could guide the development of new therapies. The work, published in Proceedings of the National Academy of Sciences, shows that some tumor cells depend on the combined action of two proteins, CDK16 and CDK18, to repair their DNA and continue multiplying. When both are inactivated, damage accumulates and the cells' ability to survive is impaired.

Medical Xpress · Nov 3
Deaths from heart valve disease rising among U.S. adults ages 65 and older

After nearly two decades of decline, valvular heart disease death rates have increased from 2018 to 2023 and are predicted to remain elevated through 2040, according to independent, new preliminary research presented at the American Heart Association's Scientific Sessions 2026, held Nov. 6–9 in Chicago.

Medical Xpress · Nov 2
Personalized score uses ten blood markers to flag disease risk and assess healthy aging

Studies conducted in various countries indicate that approximately 60% of people over age 65 currently live with two or more chronic conditions. With the aim of reversing this trend and promoting healthy aging, European researchers have created a new personalized indicator that provides a detailed snapshot of a patient's metabolism by analyzing, with high precision, the chemicals the body produces to function.

Medical Xpress · Oct 31
How mental health and cancer survivorship intersect

A Stanford Medicine study identified an often-overlooked period of vulnerability for cancer survivors: Mental health disorders identified two to five years after a cancer diagnosis were associated with a 119% higher rate of death from cancer compared with patients without documented mental disorders during the same period.

Medical Xpress · Oct 30
In Settling Fraud Case, N.Y. Medicare Advantage Insurer, CEO Will Pay Up to $100M

This is a MedPage Today story. A western New York health insurance provider for seniors and the CEO of its medical analytics arm have agreed to pay a total of up to $100 million to settle Justice Department allegations of fraudulent billing for health conditions that were exaggerated or didn't exist. Independent Health Association of Buffalo, which operates two Medicare Advantage plans, will pay up to $98 million. Betsy Gaffney, CEO of medical records review company DxID, will pay $2 million, according to the settlement agreement. Neither admitted wrongdoing. "Today's result sends a clear message to the Medicare Advantage community that the United States will take appropriate action against those who knowingly submit inflated claims for reimbursement," Michael Granston, a Department of Justice (DOJ) deputy assistant attorney general, said in announcing the settlement on December 20. Frank Sava, a spokesperson for Independent Health, said in a statement: "The assertions by the DOJ...

ABC News · Dec 28